Preprints

Denney KA, Wu MV, Sun SD, Moon S, Tollkuhn J. Comparative analysis of gonadal hormone receptor expression in the house mouse, meadow vole, and prairie vole brain. bioRxiv 2023 doi:10.1101/2023.05.12.540606

Gegenhuber B, Wu MV, Bronstein R, Tollkuhn J. Neural regulation of gene expression by estrogen receptor alpha. bioRxiv 2020 doi: 10.1101/2020.10.21.349290

Research Articles

Denney KA*, Wu MV*, Sun SD, Moon S, Tollkuhn J. Comparative analysis of gonadal hormone receptor expression in the postnatal house mouse, meadow vole, and prairie vole brain. Horm Behav 2024 Feb:158:105463. doi: 10.1016/j.yhbeh.2023.105463.

Gegenhuber B, Wu MV, Bronstein R, Tollkuhn J. Gene regulation by gonadal hormone receptors underlies brain sex differences. Nature 2022 Jun;606(7912):153-159. doi: 10.1038/s41586-022-04686-1.

Wu MV, Tollkuhn, J Estrogen receptor alpha is required in GABAergic, but not glutamatergic, neurons to masculinize behavior. Horm Behav. 2017 Sep 20;95:3-12. doi: 10.1016/j.yhbeh.2017.07.001.

Reviews and Book Chapters

Sun SED, Tollkuhn J. Regulation of gene expression in the brain by sex hormones. 2023 In (M. Legato) Principles of Gender-Specific Medicine, 4th Ed. Elsevier

Gegenhuber B, Tollkuhn J. Epigenetic Mechanisms of Brain Sexual Differentiation 2022 Cold Spring Harb Perspect Biol. 2022 Jul 11:a039099. doi: 10.1101/cshperspect.a039099.

Ruiz-Ortiz J,  Tollkuhn J. Specificity in sociogenomics: Identifying causal relationships between genes and behavior.  Horm Behav. 2021 Jan;127:104882.

Gegenhuber B, Tollkuhn J. Signatures of sex: Sex differences in gene expression in the vertebrate brain. 2020 Wiley Interdiscip Rev Dev Biol. 2020 Jan;9(1):e348.

Gegenhuber B, Tollkuhn J.  Sex Differences in the Epigenome: A Cause or Consequence of Sexual Differentiation of the Brain? Genes. 2019 Jun 7;10(6):432.

Manoli DS, Tollkuhn J. Gene regulatory mechanisms underlying sex differences in brain development and psychiatric disease. . Ann N Y Acad Sci. 2018 May;1420(1):26-45.

Collaborations

Sun Q, van de Lisdonk D, Ferrer M, Gegenhuber B, Wu MV, Park Y, Tuveson DA, Tollkuhn J, Janowitz T, Li B. Area postrema neurons mediate interleukin-6 function in cancer cachexia. Nat Commun 2024. Jun 1;15(1):4682. doi: 10.1038/s41467-024-48971-1

Degroat TJ, Wiersielis K, Denney K, Kodali S, Daisey S, Tollkuhn J, Samuels BA, Roepke TA. Chronic stress and its effects on behavior, RNA expression of the bed nucleus of the stria terminalis, and the M-current of NPY neurons. Psychoneuroendocrinology 2024 Mar:161:106920. doi: 10.1016/j.psyneuen.2023.106920.

Smiley KO, Munley KM, Aghi K, Lipshutz SE, Patton TM, Pradhan DS, Solomon-Lane TK, Sun SED. Sex diversity in the 21st century: Concepts, frameworks, and approaches for the future of neuroendocrinology Horm Behav 2024 Jan:157:105445. doi: 10.1016/j.yhbeh.2023.105445.

Aghi K, Goetz TG, Pfau DR, Sun SED, Guthman EM, Roepke TA. Using animal models for gender-affirming hormone therapy. J Endocr Soc 2023 Nov 20;8(1):bvad144. doi: 10.1210/jendso/bvad144.

Sun Q, van de Lisdonk D, Ferrer M, Gegenhuber B, Wu M, Tollkuhn J, Janowitz T, Li B. Area postrema neurons mediate interleukin-6 function in cancer-associated cachexia. bioRxiv 2023 doi: 10.1101/2023.01.12.523716

Aghi K, Goetz TG, Pfau DR, Sun SED, Roepke TA, Guthman EM Centering the needs of transgender, non-binary, and gender-diverse populations in neuroendocrine models of gender-affirming hormone therapy. Biol Pyschiatry Cogn Neurosci Neuroimaging 2022 Jul 18;S2451-9022(22)00173-2. doi: 10.1016/j.bpsc.2022.07.002. 

Luo PX, Zakharenkov HC, Torres LY, Rios RA, Gegenhuber B, Black AM, Xu CK, Minie VA, Tran AM, Tollkuhn J, Trainor BC. Oxytocin receptor behavioral effects and cell types in the bed nucleus of the stria terminalis. Horm Behav 2022 Jul;143:105203. doi: 10.1016/j.yhbeh.2022.105203.

Miyagi M, Guthman EM, Sun SED Transgender rights rely on inclusive language. Science 2021 Dec 24;374(6575):1568-1569.

Krause WC, Rodriguez R, Gegenhuber B, Matharu N, Rodriguez AN, Padilla AM, Herber, CB, Correa SM, Ahituv N, Tollkuhn J*, Ingraham HA*. Estrogen engages brain MC4R signalling to drive physical activity in female mice. Nature 2021 Nov;599(7883):131-135. doi: 10.1038/s41586-021-04010-3 *co-corresponding authors

Li S, Kendall J, Park S, Wang Z, Alexander J, Moffitt A, Ranade N, Danyko C, Gegenhuber B, Fischer S, Robinson BD, Lepor H, Tollkuhn J, Gillis J, Brouzes E, Krasnitz A, Levy D, Wigler M. Copolymerization of single-cell nucleic acids into balls of acrylamide gel Genome Res. 2020 Jan;30(1):49-61. doi: 10.1101/gr.253047.119

Ahrens S, Wu MV, Furlan A, Hwang GR, Paik R, Li H, Penzo MA, Tollkuhn J, Li B. A Central Extended Amygdala Circuit That Modulates Anxiety J Neurosci. 2018 Jun 13;38(24):5567-5583 doi: 10.1523/JNEUROSCI.0705-18.2018